While this formulation was not approved by the FDA, a similar product, Promescent, is available over-the-counter in the U.S. The spray is applied on the penile skin prior to intercourse. It is also sometimes used in advance of injected local anaesthetics for minor surgery and biopsies.Ī topical spray consisting of an aerosol formulation of lidocaine and prilocaine was evaluated under the name PSD502 for use in treating premature ejaculation. Also, it can be used to numb the skin before tattooing as well as electrolysis and laser hair removal. Specifically it is applied to prevent pain associated with intravenous catheter insertion, blood sampling, superficial surgical procedures, and topical anaesthesia of leg ulcers for cleansing or debridement. The lidocaine/prilocaine combination is indicated for dermal anaesthesia. This allows higher concentrations of anaesthetic to be formulated into the preparation and maintained during application.Ĭlinical use Indications The lidocaine/prilocaine eutectic mixture is an oil with a melting point of 18 ☌, and can be formulated into preparations without the use of a non- aqueous solvent. When mixed in equal quantities by weight, however, they form a eutectic mixture – that is the melting point of the mixture is lower than the melting points of the individual components. Separately, lidocaine and prilocaine are solid bases. The spray is manufactured by Plethora Solutions and branded as Fortacin in the UK and Recordati in the EU. As a spray, it is marketed under the name Tempe (topical eutectic-like mixture for premature ejaculation) (PSD502) that can be used by men to help with premature ejaculation. A 5% emulsion preparation, containing 2.5% each of lidocaine/prilocaine, is marketed by APP Pharmaceuticals under the trade name EMLA (an abbreviation for Eutectic Mixture of Local Anesthetics). ![]() Lidocaine/prilocaine is a eutectic mixture of equal quantities (by weight) of lidocaine and prilocaine.
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